William Lowther, 2nd Earl of Lonsdale (1787 - 1872), was an English politician. He was Lord President of the Council in 1852. He had no children; his nephew Henry succeeded to the earldom.

|- style="text-align: center;" | width="30%" |Preceded by:
The Earl of Lichfield | width="40%" style="text-align: center;" |Postmaster General
1841–1845 | width="30%" |Succeeded by:
The Earl of St Germans

|- style="text-align: center;" | width="30%" |Preceded by:
The Marquess of Lansdowne | width="40%" style="text-align: center;" |Lord President of the Council
1852 | width="30%" |Succeeded by:
The Earl Granville