Uasin Gishu District is a political region of Kenya in that country's Rift Valley. The city of Eldoret is its capitol, administrative center and commercial center. There is a large population of white immigrants from England, Scotland, South Africa and Zimbabwe (former state of Rhodesia) who came to settle and farm.

The Uasin Gishu District has a cool and temperate climate and is located on a plateau. It borders the Trans-Nzoia District.