Two ships of the United States Navy have borne the name USS Sculpin, named in honor of the sculpin, a spiny, large-headed, broad-mouthed, usually-scaleless fish of the family Cottidae.

• The first Sculpin, (SS-191), was a Sargo-class submarine, commissioned in 1939 and struck in 1944.

• The second Sculpin, (SSN-590), was a Skipjack-class submarine, commissioned in 1961 and struck in 1990.