Four United States Navy ships have been named USS Chicago, after the city of Chicago, Illinois.

• The first, Chicago (CA-14), was a protected cruiser launched in 1885 and active in World War I, later converted to a seaplane tender and then a barracks ship, finally being renamed Alton in 1928 and lost at sea while under tow in 1936.

• The second, Chicago (CA-29), was a heavy cruiser commissioned 1931 and active in World War II, until lost at the Battle of Rennell Island in January 1943.

• The third, Chicago (CA-136), was also a heavy cruiser, commissioned 1945 and later converted to a guided missile cruiser, and struck in 1984.

• The fourth, Chicago (SSN-721), is a Los Angeles-class nuclear attack submarine commissioned 1986 and still on active service as of 2005.