The St. Louis blues is a type of blues music. It is usually more piano-based than other forms of the blues, and is closely related to the jump blues, ragtime and piano blues. Typically, a small number of singers, a pianist and a few other instruments (used primarily for rhythm) make up a band.

• Jelly Roll Anderson
• Henry Brown
• Olive Brown
• Teddy Darby
• Walter Davis
• Tommy Dean
• Leothus Lee Green
• Stump Johnson
• Lonnie Johnson
• Daddy Hotcakes Montgomery
• Robert Nighthawk
• St. Louis Jimmy Oden
• Pinetop Sparks
• Henry Spaulding
• Roosevelt Sykes
• Henry Townsend
• Joe Lee Williams

See also "Saint Louis Blues (music)" for the W.C. Handy song.