Sir George Grey, of Fallodon, 2nd Baronet (1799-1882) was a perennial Whig cabinet minister in the mid-19th century, serving in the cabinets of Lord Melbourne, Lord John Russell, Lord Aberdeen, and Lord Palmerston. His grandson, Sir Edward Grey, 3rd Baronet, was a notable Foreign Secretary in the early 20th century.

|- style="text-align: center;" | width="30%" |Preceded by:
Sir James Graham, Bt | width="40%" style="text-align: center;" |Home Secretary
1846–1852 | width="30%" |Succeeded by:
Spencer Horatio Walpole

|- style="text-align: center;" | width="30%" |Preceded by:
Revived Office | width="40%" style="text-align: center;" |Secretary of State for the Colonies
1854–1855 | width="30%" |Succeeded by:
Sidney Herbert

|- style="text-align: center;" | width="30%" |Preceded by:
The Viscount Palmerston | width="40%" style="text-align: center;" |Home Secretary
1855–1858 | width="30%" |Succeeded by:
Spencer Horatio Walpole

|- style="text-align: center;" | width="30%" |Preceded by:
The Duke of Montrose | width="40%" style="text-align: center;" |Chancellor of the Duchy of Lancaster
1859–1861 | width="30%" |Succeeded by:
Edward Cardwell

|- style="text-align: center;" | width="30%" |Preceded by:
Sir George Lewis, Bt | width="40%" style="text-align: center;" |Home Secretary
1861–1866 | width="30%" |Succeeded by:
Spencer Horatio Walpole