In variable-width encoding schemes for computer character sets, a singleton is a character encoded with one unit, as opposed to characters encoded with multiple-unit sequences.
In Unicode, a singleton is a character the decomposition of which consists of a single character (e.g. the "ohm sign" (Ω) is decomposed as the "Greek capital letter omega" (Ω)).
In the wake of the popularity of the novel and movie Bridget Jones's Diary, the word has also become popular as a (self-)description of individuals without romantic partners, particularly applied to 20/30-something females. There is an undertone to this use of ignoring societal pressures towards partnerships.
In trick-taking games where suit is important, such as contract bridge and Hearts, if a hand contains only one card of a particular suit, that card is called a singleton. Certain bidding systems (notably Acol) add notional value to the hand for a short suit of this type since it exposes the possibility of trumping. Similarly, holding a "singleton Queen" (of Spades) in Hearts is a very disadvantageous position.
In Whiskysingleton describes the last cask or charge of a Whisky.
"Singleton" is the title of a short story by Greg Egan