SCA may refer to:

• Sexual Compulsives Anonymous
• Shuttle Carrier Aircraft
• Sickle cell anaemia
• Single Connector Attachment (an 80-pin SCSI disk interface used in some computer servers)
• Society for Creative Anachronism
• Student Conservation Association
• Subcarrier audio
• Subsidiary communications authority
• Svenska Cellulosa Aktiebolaget
• Swiss Cracking Association
• Heavy space cruiser, a conjectural naval designator for spaceborne heavy cruisers, modeled on the US Navy ship designation protocols
• Société en commandite par actions , a type of corporation, in France
• Sydney College of the Arts