A medicine bundle is a wrapped package used by Native Americans for religious purposes.

It is usually a collection of various items that might include seeds, pine cones, animal teeth, horse hair, rocks, crystals, a small idol, beads, bones, or anything else of relatively small size that posesses spiritual value to the bundle's owner.

A medicine bundle can be passed down generationally as an inheritance.

Medicine bundles are usually employed as a ritual aid in Shamanistic religions. The size of a medicine bundle usually varies from 2 to 14 inches in length.

The contents of a medicine bundle are generally considered holy by the tribal community, and are meant to be kept secret by the owner. Also, the contents of a medicine bundle are not meant to touch the ground. This is why they are to be securely wrapped.