Mark Lewis-Francis (born 4 September 1982) is a British sprint athlete, regarded as the top 100m sprinter in Britain. He is an Olympic gold medallist, having been part of the 4x100m relay team at the 2004 Summer Olympics.

Lewis-Francis burst onto the scene at an early age, but missed the 2000 Summer Olympics, instead competing at the world junior championships, in which he won gold. Lewis-Francis became Britain's top 100m sprinter after Dwain Chambers was banned for drug use in 2003. He failed to make the final of the 100 metres sprint at the 2004 Summer Olympics, but did run the final leg of the 4x100 metres, which Great Britain narrowly won by virtue of better baton hand-overs than the American favourites who finished second by 0.01 seconds outside the winning time of 38.07 seconds. The gold medal team consisted of Lewis-Francis, Marlon Devonish,Darren Campbell and Jason Gardener.