MSP is a three-letter abbreviation and has several meanings, including

• Shorthand for the Twin Cities area of Minneapolis-St. Paul, Minnesota
• The IATA airport code for Minneapolis-St. Paul International Airport
• The code for a former NOAA weather radar installation in the MSP area. Superseded by MPX .
• Member of the Scottish Parliament
• Abbreviation of Medical Services Plan
• Music Signal Processing, from the software Max/MSP. Related to DSP (Digital signal processing).
• In computing, an operating system from Fujitsu.
• Abbreviation of Medicare Secondary Payer (or Payor)
• Abbreviation of Managed Service Provider
• Movement of Society for Peace, an Algerian political party