Lule älv (English: Lule River) is a major river in Sweden, rising in northern Sweden and flowing southeast for 450 km (280 miles) before reaching the Gulf of Bothnia at Luleå.

The river is an important source of hydroelectric energy, with major hydroelectric plants at Porjus and Harsprånget . It is also used extensively for the transportation of timber, with logs floated downstream for processing at Luleå.