Loup Creek and Deepwater Railway was a short line logging railroad founded in Fayette County, West Virginia by William Nelson Page in 1896. It extended from from an interchange point at Deepwater, West Virginia with the Chesapeake and Ohio Railway (C&O) on the south bank of the navigable Kanawha River a distance of about four miles up a steep grade into the mountainous terrain southward, following the winding Loup Creek to reach a sawmill at Robson which was owned by the Loup Creek Estate. It was operated by the C&O under a verbal agreement.

In 1898, the name was changed to become the Deepwater Railway, and an extension was planned to reach nearby coal deposits in the general area of Glen Jean .

The Loup Creek and Deepwater Railway and the Deepwater Railway were predecessors of the Virginian Railway and Norfolk and Western Railway, and today form part of Norfolk Southern Corporation's rail network in North America.

See also

• William Nelson Page
• Deepwater Railway
• Building the Virginian Railway
• Virginian Railway