Academia

• Henry Louis Gates, Jr., professor and department chairman, and his wife, Sharon Adams

Business

• Rocky Aoki , restaurateur (the Benihana chain) and his wife
• Edgar Bronfman, Jr., Seagram Company CEO, and his former wife Sherry Brewer Bronfman, actress
• Andrea Jung, Avon products, and husband Michael Gould
• Robert Kiyosaki, Rich Dad Company, and wife Kim
• Russell Simmons, record producer, and wife Kimora Lee Simmons, model

Entertainment

• Woody Allen and wife Soon-Yi Previn
• Rowan Atkinson, comedian, and his wife, Sunetra Sastry
• Bai Ling, actress, and partner Chris Isaak
• Josephine Baker dancer, and her husband
• Harry Belafonte, singer and his wife Julie
• David Bowie and wife Iman
• Nicolas Cage and wife Alice Kim
• Michael Caine, actor, and his wife Shakira (née Shakira Baksh)
• Diahann Carroll, actress and former husband Vic Damone, singer
• Dave Chappelle, comedian, and his wife
• Rosalind Chao, actress, and husband Simon Templeman
• Maggie Cheung, actress and (1) ex-husband Olivier Assayas (married 1998-2001) and (2) partner Guillaume Brochard
• Tommy Chong, comedian, and former wife Maxine Sneed (married 1960-1970)
• Christy Chung, actress, and ex-husband Glen Ross
• Tyne Daly and husband George Sanford Brown
• Sammy Davis, Jr. and wife May Britt (1960-1968)
• Robert De Niro, actor, and his former wife
• Taye Diggs and wife Idina Menzel
• Katherine Dunham, dancer and her husband, John Pratt, producer
• Dawn French, comedienne and husband Lenny Henry, comedian
• Whoopi Goldberg and (1) Ted Danson actor, (2) partner Frank Langella, actor
• Lena Horne and husband Lennie Hayton
• C. Thomas Howell, actor, and his former wife, Rae Dawn Chong, actress (married 1989-1990)
• Julio Iglesias, singer and his former wife Isabel Preysler (divorced 1985)
• Quincy Jones and wife Peggy Lipton
• John Lennon and wife Yoko Ono (married 1969-1980)
• Lucy Liu, actress, and fiancé Zack Helm
• Jennifer Lopez, singer and (1) former partner Puff Daddy rap artist, (2) former fiance Ben Affleck, actor
• Yo-yo Ma, cellist, and his wife Jill Hornor, violinist
• Thandie Newton, actress and husband Oliver Parker, director
• Sandra Oh, actress, and husband Alexander Payne, director
• Linda Park, actress, and partner Tom Hardy
• Sidney Poitier and his wife Joanna Shimkus
• Diana Ross and ex-husband Robert Silberstein (1971-1976), Arne Naess
• Roxie Roker, actress and husband Sy Kravitz , producer
• Mort Sahl, comedian, and first wife China Lee, Playboy playmate
• Seal, singer, and his partner, Heidi Klum, model
• John Simmons , bassist and his wife
• Wesley Snipes and wife Nikki Park
• Mathieu Kassovitz and wife Julie Mauduech
• Tina Turner and partner Erwin Bach

Politics

• Kofi Annan, UN Secretary General, and wife Nane Annan
• Carol Moseley Braun, former United States Senator and Ambassador to New Zealand, and her husband, Michael Braun (married from 1973 to 1986)
• John Ellis (‘Jeb’) Bush, Florida Governor, and his wife, Columba
• Bob Carr, Australian New South Wales Premier and his wife, Helena
• Elaine Chao, US Secretary of Labor, and husband Mitch McConnell, Kentucky senator
• Adrienne Clarkson, Canadian Governor General, and husband John Ralston Saul
• Frederick Douglass, American abolitionist and his wife, Helen Pitts
• Joschka Fischer, German Minister of Foreign Affairs, and wife Minu Barati
• Rajiv Gandhi, Indian politician, and wife Sonia Gandhi, politician
• Phil Gramm, United States Senator, and wife Wendy Lee
• Jack Layton, Canadian NDP Leader, and wife Olivia Chow
• Chai Ling, Tiananmen protestor, and husband Robert A. Maginn Jr.
• Sir Seretse Khama, first President of Botswana, and his wife Ruth (née Williams).
• David Wu, United States Congressman (D-OR), and wife Michelle.

Law

• Richard and Mildred Loving Loving v. Virginia
• John G. Lawrence and Tyron Garner Lawrence v. Texas
• Clarence Thomas, United States Supreme Court Justice and his wife Virginia

Literature

• Isabel Allende, writer, and her husband Willie Gordon
• Amiri Baraka (aka Leroi Jones), poet and his wife Hettie Jones writer (married 1960-1965)
• Iris Chang, writer, and husband Brett Douglas
• Leslie Charteris(Leslie Charles Bowyer Yin), writer, and wives Pauline Schishkin, Barbara Meyer, Elizabeth Bryant Borst, Audrey Long
• Alexandre Dumas, fils, novelist and (1) his wife Nadeja Naryschkine (deceased) (2) his wife Henriette Régnier
• Alexandre Dumas, père (Dumas Davy de la Pailleterie), novelist and (1) his wife Ida Ferrier, actress (2) his mistress, Marie-Catherine Labay, dressmaker
• Le Ly Hayslip , author, and husband
• Gish Jen and husband David O'Connor
• Maxine Hong Kingston, writer and husband Earll Kingston
• Evelyn Lau, poet, novelist, and W. P. Kinsella, novelist
• C.Y. Lee , writer, and late wife Joyce
• Bette Bao Lord , writer, and husband Winston Lord
• Walter Mosley, writer, and his wife Joy Kellman, dancer and choreographer
• Aleksandr Sergeyevich Pushkin, author, and his wife Natalya Goncharova
• George Schuyler , author and journalist, and his wife Josephine Cogdell, artist
• Amy Tan, writer, and husband Lou De-Mattei
• Alice Walker, novelist, and her former husband Mel Leventhal
• Michelle Sagara West, writer, and husband
• Lois-Ann Yamanaka, author, and husband John Inferrera
• Zhai Zhenhua, writer, and husband Charles B. Daniels

Media

• Emanuel Ax, pianist, and wife Yoko Nazaki
• Julie Chen, newscaster, and husband Les Moonves
• Connie Chung, newscaster and husband Maury Povich, TV personality
• Roger Ebert, film critic and author, and his wife Chaz Hammersmith
• Michelle Malkin, journalist, and her husband
• Rupert Murdoch, media proprietor, and wife Wendi Deng
• Shadoe Stevens, TV & Radio presenter and his wife
• Miyuki Tanobe, painter, and husband Maurice Savignac
• Montel Williams, TV personality and his wife

Military

• Claire Chennault, aviator, and wife Anna Chan Chennault
• Charles Robert Jenkins and wife Hitomi Soga

Science

• Steven Chu, Nobel Laureate Physicist, and wife Jean Chu
• Fan Chung, mathematician and husband Ronald Graham, mathematician
• Samuel C. C. Ting, Nobel Laureate Physicist, and (1) ex-wife Kay Kuhne; (2) wife Dr. Susan Carol Marks
• Daniel C. Tsui, Nobel Laureate Physicist, and wife Linda Varland

Sports

• Boris Becker, tennis player, and his wife Barbara
• Kobe Bryant, professional basketball player, and his wife Vanessa Laine
• Michelle Kwan, figure skater, and partner Brad Ference, NHL hockey player
• Bruce Lee, martial artist and actor, and his wife Linda
• Debbie Thomas , skater, and her husband
• Tiger Woods, golfer, and his wife Elin Nordegren
• Kristi Yamaguchi, skater, and husband Bret Hedican, hockey player

Royalty

• Prince Joachim of Denmark and Princess Alexandra
• The King (Chogyal) of Sikkim and Hope Cooke
• King Hussein of Jordan and (1) Princess Muna, (2) Queen Noor
• Prince Maximilian of Liechtenstein and fashion designer Angela Brown

Other Notable Personalities

• Leroy Chiao, Astronaut, and wife Karen
• Oscar de la Renta, designer, and his wife Annette, socialite
• Diana, Princess of Wales and (1) Dr. Hasnat Khan, (2) companion Dodi al-Fayed
• Gloria Rubio y Alatorre, (better known as Gloria Guinness), socialite and (1) husband Count Franz Egon von Fürstenberg-Herdringen, aristocrat (2) husband Ahmed Fakhri , aristocrat and (3) Group Capt. Thomas Loel Guinness , Member of Parliament and Guinness heir
• Vera Wang, fashion designer, and husband Arthur Becker

Historical

• Alexander the Great and his wife Roxana of Persia
• Fletcher Christian, sailor and mutineer, and his Tahitian wife Maimiti
• Marquis Antoine-Alexandre Davy de la Pailleterie , France’s Commissaire Général in the Artillery in the colony of Santo Domingo (Haiti), and his wife Marie-Céssette Dumas, a slave
• General Thomas-Alexandre Dumas (Thomas-Alexandre de la Pailleterie) and his wife Marie-Louise Elizabeth Labouret
• Ibrahim Abram Petrovich Gannibal , abducted Abyssinian noble, later courtier to Peter the Great, and (1) his wife (?) (divorced), (2) his wife Christina-Regina Scherberg
• Thomas Jefferson and Sally Hemings, his slave (hotly debated; DNA evidence of their purported offspring is open to interpretation)

Fictional

• Isaac Dan der Grimnebulin, Human, and Lin, Khepri, Perdido Street Station characters
• Harry Potter and love interest Cho Chang
• William Riker, human and Deanna Troi, Human-Betazoid, Star Trek characters
• Ambassador Sarek of Vulcan and his Human wife Amanda Grayson, Star Trek characters
• Amy Wong and Kif Kroker, Futurama characters

Notorious inter-ethnic couples

• Rose Porteous, socialite, and (1) her late husband Lang Hancock (2) her present husband, Willie Porteous
• O.J. Simpson and his wife the late Nicole Brown Simpson
• Marie-Joseph Angelique, Canadian slave and her lover Claude Thibault
• Michael Jackson and (1) his wife Lisa Marie Presley (2) his wife Debbie Rowe