Kenneth "Supreme" McGriff is a famous drug dealer and leader of The Supreme Team, loosely portrayed by Wesley Snipes in New Jack City. He served ten years for a 1989 drug conviction. When released, he helped finance the popular rap label Murder Inc. with neighborhood associate Irv Gotti. McGriff has been arrested two more times since then for parole violations for possessing firearms. He was part of the major indictment on Murder Inc. in 2003, which exposed its more criminal side. McGriff is currently on trial with several other men for a litany of federal crimes including murder, drug dealing, and money laundering.

One of the most feared black gangsters of all time, McGriff is alleged to have a hand in the (possibly drug related) murder of Run D.M.C. DJ Jam Master Jay, and the shootings of 50 Cent, a former "employee" of his. He allegedly felt 50 had exposed just a little too much on the kingpin of Jamaica, Queens in his 2002 mixtape song "Ghetto Qua'ran".