Jennifer Syme, (December 7, 1972 – April 2, 2001), was an entertainment industry employee, best known as the companion of actor Keanu Reeves.

Born Jennifer Maria Syme in Pico Rivera, California, she was working as an assistant to film director David Lynch when she began dating actor Keanu Reeves. Syme had performed in a few minor film roles including for Lynch in his Lost Highway.

In December of 1999 she was expecting their daughter, to have been named Eva Archer Syme-Reeves, when the infant was still-born a few weeks premature. The photo depicted here is of Syme and Reeves attending the internment at the Westwood Village Memorial Park Cemetery in Los Angeles.

Syme's relationship with Reeves ended shortly after the child's death but they remained friends until her own untimely passing as a result of an automobile accident in the spring of 2001 in Los Angeles. Jennifer Symes was buried next to her daughter.

In tribute, David Lynch dedicated his film Mulholland Dr. to her memory.