Henry Somerset, 1st Marquess of Worcester (bef. 1590 - 18 December 1646) was the son of Edward Somerset, 4th Earl of Worcester and Elizabeth Hastings . On March 3rd, 1628, he succeeded his father and became the 5th Earl of Worcester. For his supporting of King Charles II Stuart in his restoration, he was created 1st Marquess of Worcester on November 2nd, 1642. He married Anne Russell on June 16th, 1600. Somerset died in on December 18th, 1646.

With his wife, he had one son, Edward Somerset, 2nd Marquess of Worcester, his heir and successor, and he had one illegitimate son, Sir John Somerset, who married Hon. Mary Arundell , a daughter of the 1st Baron Arundell of Wardour, co. Wiltshire by his second wife.