HE, He, or he may stand for:

• a third person singular English language pronoun for a male.
• a third person singular English language pronoun indicating unknown gender.
• Hebrew language (ISO 639 alpha-2, he)
• the letter He in the Hebrew alphabet
• Helium (He), symbol for the chemical element
• Hé, a Chinese family name represented by the character 何
• He, an alternative name for tag.
• Higher Education (HE)
• High Explosive is also commonly represented by this initialism.
• Hollis and Eastern Railroad – AAR reporting mark HE