Dimethoxyethane, also known as glyme, monoglyme, dimethyl glycol, ethylene glycol dimethyl ether, dimethyl cellosolve, and DME, is a clear, colorless, and liquid ether that is used as a solvent. Dimethoxyethane is moderately soluble in water (10 g/100 ml).

Dimethoxyethane is often used as a higher boiling alternative to diethyl ether and THF. Dimethoxyethane forms chelate complexes with cations and acts as a bidentate ligand. It is therefore often used in organometallic chemistry like Grignard reactions, hydride reductions , and palladium catalyzed reactions like Suzuki reactions and Stille coupling . Dimethoxyethane is also a good solvent for oligo- and polysaccharides.

Dimethoxyethane is also used as solvent for electrolytes of lithium batteries.

See also

• Ether
• Ethylene glycol
• Dioxane

External links

• http://www.glymes.com/monoglyme.php
• Chemical hazard links