Gerard Brandon (September 15, 1788 — March 28, 1850) was an American political leader who twice served as Governor of Mississippi during its early years of statehood.

Brandon became governor for the first time upon the death of Walter Leake, serving from Leake's death on November 17, 1825 until January 7, 1826, when David Holmes, the last territorial governor and first governor of the State of Mississippi was again inaugurated as governor. Brandon became governor of Mississippi again on July 25, 1826 and served until January 9, 1832.