Georg Friedrich Hohenzollern, Margrave of Brandenburg-Ansbach and Bayreuth, and Regent of Ducal Prussia was born 1539 and died 1603. He was the son of Georg Margrave of Brandenburg-Ansbach, a member of the Hohenzollern dynasty (1484-1543).

Georg Friedrich reigned in Ansbach and Jaegerndorf since 1556 and after the death of his cousin Alcibiades in 1557 also in Bayreuth.

He took over the administration of Ducal Prussia in 1577, when the then-reigning duke (Albert Frederick) became ill.

He was the last of the older Frankish line of the House of Hohenzollern. Upon his death Ansbach and Bayreuth were inherited according to the Gera house treaty of 1598 by younger princes of the Brandenburg line.

|- style="text-align: center;" | width="30%" |Preceded by:
Albrecht Alcibiades | width="40%" style="text-align: center;" |Fürst von Bayreuth
1553–1603 | width="30%" |Succeeded by:
Christian