Fist can refer to the following:

• The term used to describe the clenched hand when the fingers are curled into the palm and the thumb is retracted. This is typically used in unarmed combat, such as fist-fighting.
• The raised, clenched fist is used as a gesture of defiance in some cultures.
• The 1978 film F.I.S.T..
• Fisting is the act of the inserting fingers or even the whole hand in a vagina or rectum for sexual pleasure.