Chylomicrons are large lipoprotein particles that are created by the absorptive cells of the small intestine. Chylomicrons transport lipids to adipose tissue where they are broken down by lipoprotein lipase. The way from the intestines to the adipose tissue is this: The chylomicrons are released by exocytosis from enterocytes into lacteals, lymphatic vessels originating in the villi of the small intestine, and are then secreted into the bloodstream, at the place where the lymphatic system falls into the blood system , at the thoracic duct's connection with the left subclavian vein .