Ceruloplasmin (or caeruloplasmin), officially known as ferroxidase or iron(II):oxygen oxidoreductase, is a copper transport protein found in the blood. It is an enzyme (EC 1.16.3.1).

Interpretation

Decreased levels

Lower than normal ceruloplasmin levels may indicate:

• Menkes' syndrome (Menkes' kinky hair syndrome) (very rare)
• Wilson's disease (a rare copper storage disease)

Elevated levels

Greater than normal ceruloplasmin levels may indicate:

• pregnancy
• lymphoma
• acute and chronic infections (it is an acute phase reactant)
• rheumatoid arthritis

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