Doctor Barnett Slepian (April 23, 1946 - October 22, 1998) was a physician in Amherst, New York in the United States who was murdered in his home by an anti-abortion activist, James Charles Kopp. Slepian was one of several physician, nurses, and health care workers, killed or injured by Anti-abortion activists.

Slepian was an obstetrician/gynecologist with his own practice, but he also provided services at a local clinic, GYN Women's Services.

On October 22, 1998, Slepian had returned from synagogue and was preparing soup in his kitichen when he was shot in the back through a window. He died a few hours later at the age of 52. Kopp fled, but was arrested in France. He was tried and convicted in Buffalo, New York and is currently serving a term of imprisonment.