This article is about the mother of Amphion, for other things and people (including Greek Myths about people) named Antiope, see Antiope (disambiguation).

Antiope was also the name of the daughter of King Nycteus of Thebes or the river-god Asopus. Zeus impregnated her and she fled in shame to King Epopeus of Sicyon and abandoned her children, Amphion and Zethus. They were exposed on Mount Cithaeron , but were found and brought up by a shepherd. Nycteus, unable to retrieve his daughter, sent his brother Lycus to take her. He did so and gave her as a slave to his own wife, Dirce.

Amphion became a great singer and musician after Hermes taught him to play and gave him a golden lyre, Zethus a hunter and herdsman. They punished King Lycus and Queen Dirce for cruel treatment of Antiope, their mother, whom was treated as a slave. Dirce was tied to the horns of a bull as revenge. They built and fortified Thebes, huge blocks of stone forming themselves into walls at the sound of Amphion's lyre. Amphion married Niobe, and killed himself after the loss of his wife and children. Zethus married Aedon, or sometimes Thebe. The brothers were buried in one grave.