American Connection is a brand name used by three airlines feeding American Airlines's hub at Lambert-Saint Louis International Airport:

• Chautauqua Airlines, serving 14 cities with 15 Embraer ERJ-140 jets
• Corporate Airlines , serving 13 cities with 12 Jetstream 31 turboprops
• Trans States Airlines, serving 29 cities with 15 Embraer ERJ-145s, 13 Jetstream 41s, one ATR-42 and one ATR-72.

Unlike American Eagle, which feeds other AA hubs, American Connection is independently owned and operated. The American Connection carriers previously operated under a marketing agreement with Trans World Airlines as "TWExpress."

Together, the three carriers operate over 300 flights a day to 49 destinations.

Disasters

• Corporate Airlines Flight 5966 crashed on October 20 near Kirksville, Missouri killing 13 people, with two survivors.

Destinations

• Atlanta Hartsfield International Airport (CH, TS)
• Austin Bergstrom International Airport (TS)
• Bloomington, Illinois (TS)
• Boston Logan International Airport (CH)
• Burlington, Iowa (CP)
• Cape Girardeau, Missouri (CP)
• Cedar Rapids, Iowa (TS)
• Champaign, Illinois (TS)
• Charlotte Douglas International Airport (TS)
• Cincinnati Northern Kentucky International Airport (TS)
• Colorado Springs Airport (TS)
• Columbia, Missouri (TS)
• Columbus Port Columbus International Airport (TS)
• Dayton James M. Cox International Airport (CH)
• Decatur, Illinois (TS)
• Denver International Airport (CH, TS)
• Des Moines, Iowa International Airport (TS)
• Evansville, Indiana (CP)
• Fayetteville, Arkansas (TS)
• Fort Leonard Wood, Missouri (CP)
• Hartford Bradley International Airport (TS)
• Indianapolis International Airport (TS)
• Jackson, Tennessee (CP)
• Jacksonville International Airport (TS)
• Joplin, Missouri (TS)
• Kirksville, Missouri (CP)
• Madison, Wisconsin (TS)
• Marion, Illinois (CP)
• Memphis International Airport (TS)
• Milwaukee General Mitchell International Airport (CH, TS)
• Minneapolis-St. Paul International Airport (CH)
• Nashville International Airport (CH, CP, TS)
• New Orleans International Airport (TS)
• Newark International Airport (CH, TS)
• Norfolk, Virginia (CH)
• Oklahoma City Will Rogers World Airport (TS)
• Orlando International Airport (CH)
• Owensboro, Kentucky (CP)
• Paducah, Kentucky (CP)
• Peoria, Illinois (TS)
• Philadelphia International Airport (CH, TS)
• Quincy, Illinois (CP)
• Raleigh-Durham International Airport (CH, TS)
• San Antonio International Airport (CH)
• Springfield, Illinois (TS)
• Springfield, Missouri (TS)
• Tampa International Airport (CH)
• Washington Dulles International Airport (CH)
• Washington Reagan National Airport (TS)
• Wichita, Kansas (CH)