AFA may stand for:

• Action for Animals
• afghani, the currency of Afghanistan
• Alternating finite automaton in computer science
• Amateur Football Alliance
• American Family Association
• American Federation of Aviculture
• Argentine Football Association
• Association of Flight Attendants
• Anti-Fascist Action
• Antifascistisk aktion - a Swedish antifa group
• Afro-Asiatic languages (ISO 639 alpha-3, afa)

AFA was also the name of a Spanish automobile manufacturer.