The acronym ACE, depending on context, can refer to:

• Accumulated Cyclone Energy, a measure of the activity of Atlantic hurricane seasons
• Adaptive Communication Environment, an open-source class framework
• Advanced Composition Explorer, a NASA satellite
• Air Combat Emulator , a 1980s computer game for the Commodore 64 home computer
• Altamont Commuter Express, a commuter train service in California (Stockton–San Jose)
• American Council on Education
• Angiotensin-converting enzyme
• Armored Combat Earthmover (M9)
• ASCII Compatible Encoding, in the context of IDNA
• Automatic Computing Engine, a 1952 British computer
• ACE - the IATA code for the airport at Lanzarote, Canary Islands.
• The ISO 639 code for the Achinese language

See also

• Ace