143 Adria is a fairly large main belt asteroid. This dark-coloured asteroid has probably a primitive carbonaceous chondritic composition.

It was discovered by J. Palisa on February 23, 1875 and named after the Adriatic Sea, on the coast of which the discovery was made.

One occultation by Adria has been reported so far, from Japan on August 21, 2000. A somewhat spherical shape measuring 98 × 86 km was observed.